The chapel, built with a square base and a golden dome, serves as the final resting place for its founder King Sigismund, as well as King Sigismund II Augustus and Anna Jagiellon. Inside, the tombs are adorned with sculptures, stuccos, and paintings crafted by some of the most renowned artists of the time, such as architect Berrecci, Georg Pencz, Santi Gucci, and Hermann Vischer.
Considered by many art historians as a masterpiece of Tuscan Renaissance, it was financed by King Sigismund I the Old and constructed between 1519-1533 by Italian architect Bartolomeo Berrecci.